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McCain Withdraws Dietary Supplement Safety Act

By Jack Owoc
CEO VPX/Redline

Julius Caesar once declared, "Veni, Vidi, Vici! -- "I came, I saw, I conquered" to assert his victory and remind the senate of his military prowess. Ironically, today it is the American people who have declared, Veniebamus, Videbamus, Vincemus! - We Came, We Saw, We Conquered to remind the senate of the power of the people of the greatest nation to ever walk planet Earth --The People of United States of America!

VPX/Redline would like to thank everyone for their support in responding to our request to take action by e-mailing a letter to John McCain. All of you who took your precious time and take action stopped the so called, "Dietary Supplement Safety Act of 2010, S. 3002" dead in its tracks! The anti-supplement bill, "S. 3002" was offered this February and crushed less than one month later last Thursday, March 4, 2010! You made your voices heard loud and clear and congress listened! There's been no official tally but my guess is that millions of you objected via e-mail to this proposed highly suppressive bill.

The fact is that American consumers love their dietary supplements and want less, not more regulation. We want less of Big Pharma trying to force drugs down our throats and more sophisticated and efficacious supplements. The Dietary Supplement Safety Act of 2010, S. 3002 would cripple dietary supplement innovation like the Codex Alimentarius has in Europe and other parts of the world. The Codex Alimentarius makes criminals out of ordinary persons like yourself who want to use dietary supplements to improve health, vitality and performance. "Codex" is a global political and pharmaceutical drug cartel designed to hand over the control of natural supplements to the pharmaceutical giants. The Dietary Supplement Safety Act of 2010, S. 3002 would be the foundation to launch the Codex Alimentarius right here in America and give drug companies and the government the right to destroy what health freedoms DSHEA has accomplished. The fact that American consumers love their dietary supplements and want less, not more regulation is proven by the hard data demonstrating that in one of the worst economies in decades dietary supplement sales increased significantly in 2009! During America's financial crisis in 2008 and 2009 the dietary supplement industry was one of our nation's only industries that had economic growth. The passing of any bill that would jeopardize the dietary supplement industry is counter to the health, best interest and desire of American citizens. Furthermore, the passing of any bill so highly detrimental to the USA's economic growth and well being and is outright ANTI-AMERICAN!

In closing I'd like to thank you again for your pro-active support in stopping the "Dietary Supplement Safety Act of 2010, S. 3002" DEAD IN ITS TRACKS! Dietary supplements are 100 times safer than OTC drugs, pharmaceutical drugs, tobacco and alcohol and, therefore, these are the industries that congress needs to be focusing on, cleaning up and making safer!

If law enforcement did their job and arrested the persons involved in adulterating dietary supplements with steroids and sex drug analogs, this challenge would have been solved long ago and there would be no issue. Professional sports and the Olympics have major problems with steroids and a myriad of other performance enhancing and muscle building drugs. In conjunction with anti-doping institutes, these organizations work together to deceive the world by blaming dietary supplements for their organization's drug epidemic. The citizens of America and the Dietary Supplement industry are sick of these lies and demand an end to this mass deception immediately. Shouldn't the Olympic Committee be focusing on the death and massive injuries during the 2010 Winter Olympics instead of lying to the world about dietary supplements?

Between all the industries involved in dietary supplements including functional beverages in regard to freight, all aspects of shipping, gas, retail and wholesale sales, distribution, packaging, manufacturing, trade shows, health food stores like GNC, Vitamin Shoppe, Vitamin World, big box stores like Walgreens, CVS, WalMart, grocery stores, C-Stores like 7-Eleven, and workout facilities like Bally's Fitness and 24 Hour Fitness, our economy would lose billions of dollars if an anti-supplement bill like this was passed into law. Therefore I declare all organizations and individuals who threaten the great Dietary Supplement Industry as UNAMERICAN! WE THE PEOPLE DEMAND AN END TO YOUR TOMFOLLERY!

I will be calling staunch dietary supplement supporter, Senator Hatch this week to set up a meeting to strengthen DSHEA on behalf of all Americans and on behalf of the wellbeing and recovery of the American economy! For an update, log on to vpxsports.com or check out my wall on Facebook. May God Bless you and never forget March 4, 2010 - the day, Veniebamus, Videbamus, Vincemus! - We Came, We Saw, We Conquered!

Bisphenol A levels in cans triggers call for ban

Redline (VPX) CEO, Jack Owoc has already exposed that the carbonation in colas and energy drinks can leech calcium from bones and their high sugar content is a major contributor in making America the fattest nation ever to walk planet Earth. Now these canned concoctions have another health concern called bisphenol. Read the link below for, yet, another reason to consume VPX's, Protein Rush muscle building beverages, Redline Energy Drinks and Redline Shots, and Meltdown Fat Burning Drinks--NO carbonation, NO sugar and NO bisphenol:

Bisphenol A levels in cans triggers call for ban

VPX/Redline rolling into the Arnold Schwarzenegger Sports Fitness Expo

	Mr. Jack Owoc, "Why isn't VPX/Redline rolling into the Arnold Schwarzenegger Sports Fitness Expo this weekend with its usual entourage of 75 fitness professionals?"
	The vendors need a new and preferably more affluent demographic to market to. They need to move the Arnold to the North East or a big city within easy proximity of millions of NEW and fresh consumers like Chicago. VPX/Redline spends in excess of $350,000 every year to bring a crew of 75 fitness personnel to serve at the Arnold and give out 50,000 bags with 5 samples and a magazine – that's 300,000 freebees plus the biggest custom made bag – all for the consumer to have a great fitness experience. Team VPX/Redline humbly and graciously works our butts off for the muscle building community! After the Arnold Schwarzenegger promoters told VPX/Redline that we couldn't have our big booth unless we sponsored the show for another $30,000, we declined their offer and gracefully said, "No thanks"! Consequently, because of greed, the Columbus economy loses $350,000 and the Arnold Schwarzenegger Expo attendees lose the dedicated attention of 75 trained bodybuilding and fitness professionals and 300,000 free samples.

VITA-SCARE 2010: The McCain Assault on Vitamins and Supplements

McCAIN’S “S.3002”: WHAT IS IT?
	John McCain’s legislation would effectively, literally, allow the federal government to take-over America’s vitamin and nutritional supplement industry!
	ALL vitamins, minerals, herbal products and nutritional supplements currently allowed under federal law could be removed from the market under John McCain’s bill.
	For the first time in history, even RETAILERS who sell vitamins and nutritional products would be required to REGISTER with the federal government… and obtain proof (at their own expense) that products they sell meet all new government regulatory requirements… or be subject to penalties as high as TWICE THEIR PROFIT!
J.D. HAYWORTH: HOW HE WILL HELP!
	J.D. HAYWORTH is a strong supporter of the 90% of Americans, including seniors and children, who took a vitamin, nutritional supplement, or health product of some kind last year!
	J.D. HAYWORTH is a staunch defender of DSHEA, the federal law currently governing the vitamin and supplement industry, and he’ll work to protect the industry, and the American people, as Arizona’s next U.S. Senator!

"This is a direct assault on American business and on American consumers, especially seniors and kids, who depend on vitamins and nutritional supplements,” says J.D. Hayworth. "In the Senate, I’ll work to protect the people and this industry, not put it out of business." J.D. Hayworth, Arizona’s next U.S. Senator, needs YOUR support! Please visit www.JDforSENATE.com to donate today!

Contributions to JD Hayworth 2010 are not deductible as charitable contributions for federal income tax purposes. An individual may contribute up to $2,400 for the primary election and up to $2,400 for the general election. Federal multicandidate PACs may contribute up to $5,000 for each election. Contributions from corporations, labor unions, federal-government contractors, and foreign nationals (non-green-card holders) are prohibited. *Federal law requires JD Hayworth 2010’s best efforts to obtain, maintain, and report the name, address, occupation, and employer of any individual who contributes more than $200 in an election cycle.

Paid for by JD Hayworth 2010

DON’T LET CONGRESS TAKE AWAY YOUR SUPPLEMENTS

On February 3, 2010, Senators John McCain and Byron Dorgan introduced S. 3002, a bill entitled, The Dietary Supplement Safety Act. The supposed purpose of the bill is to make dietary supplements "safer." This is ironic because dietary supplements are already hundreds of times safer than either prescription or over-the-counter drugs.

The real purpose of this bill is to limit your access to dietary supplements. The government would tell you, the consumer, what dietary supplements you could and could not buy. There is little doubt that if this bill becomes law your choices will be drastically reduced, and many of the supplements you take today will become illegal. This misguided bill affects ALL dietary supplements, including vitamins, minerals, herbs, sports and diet products. There is also little doubt that if this bill becomes law GNC will suffer severe financial hardship and may be faced to close its doors forever.

But, who is behind this bill? The answer is simple: big time sports leagues, especially Major League Baseball, which in recent years have been plagued by steroid scandals. Fearful that Congress will end their lucrative anti-trust exemption and require real drug testing, they have decided to make the supplement industry their scapegoat. When one of their players tests positive for steroids, they'd like people to think it must have been an adulterated dietary supplement.

Unless you want the government to tell you what supplements you can and cannot take, and unless you want to see your freedom of choice drastically reduced, you need to make your views known to your United States Senators. Tell them to oppose this terrible piece of legislation.

To make your views known, you can go to the Save Our Supplements website (SaveOurSupplements.org) to send a note in opposition to S. 3002 directly to your two Senators or you can use the website to get information to construct your own personal letter. Either way, you need to act immediately. Do not let Congress take away your right to buy and use dietary supplements.

Click here to go to the site and write your Senators.

For More Information:

• www.dshea.org
• www.crnusa.org
• www.unpa.com
• www.naturalproductsassoc.org
• senators_phone_list.pdf 

A High Protein Diet With Resistance Exercise Training Improves Weight Loss And Body Composition In Overweight And Obese Patients With Type 2 Diabetes

Once again proving that eating MORE PROTEIN IS GOOD FOR YOU! In addition to being the creme de la creme of muscle building nutrients, it helps folks with diabetes too!

Published online before print February 11, 2010, doi: 10.2337/dc09-1974

A High Protein Diet With Resistance Exercise Training Improves Weight Loss And Body Composition In Overweight And Obese Patients With Type 2 Diabetes

• 1. Thomas P Wycherley, BSci (Hons)¹,²,
• 2. Manny Noakes, PhD¹,
• 3. Peter M Clifton, PhD¹,
• 4. Xenia Cleanthous, MND¹,
• 5. Jennifer B Keogh, PhD¹ and
• 6. Grant D Brinkworth, PhD¹

+ Author Affiliations

•1.       ¹Preventative Health Flagship, Commonwealth Scientific and Industrial Research Organisation - Food and Nutritional Sciences, Adelaide, Australia

•2.       ²Department of Physiology, School of Molecular and Biomedical Science, University of Adelaide, Adelaide, Australia

Abstract

Aim: Evaluate the effects of two low fat hypocaloric diets differing in carbohydrate:protein ratio, with and without resistance training (RT), on weight loss, body composition and cardiovascular disease (CVD) risk outcomes in overweight/obese patients with type 2 diabetes (T2D).

Methods: 83 men/women with T2D (age:56.1±7.5yrs, BMI:35.4±4.6kg/m²) were randomly assigned to an isocaloric, energy restricted diet (females:6 MJ/day, males:7 MJ/day) of either standard carbohydrate (CON; carbohydrate:protein:fat, 53:19:26) or high protein (HP; 43:33:22), with or without supervised RT (3d/wk) for 16-wks. Body weight and composition, waist circumference (WC) and cardiometabolic risk markers were assessed.

Results: 59 participants completed the study. There was a significant group effect (P≤0.04) for body weight, fat mass and WC with greatest reductions in HP+RT; weight (CON:-8.6±4.6kg, HP:-9.0±4.8kg, CON+RT:-10.5±5.1kg, HP+RT:-13.8±6.0kg), fat mass (CON:-6.4±3.4kg, HP:-6.7±4.0kg, CON+RT:-7.9±3.7kg, HP+RT:-11.1±3.7kg), WC (CON:-8.2±4.6cm, HP:-8.9±3.9cm, CON+RT:-11.3±4.6cm, HP+RT:-13.7±4.6cm). There was an overall reduction (P<0.001) in fat-free mass:-2.0±2.3kg, blood pressure:-15/8±10/6mmHg, glucose:-2.1±2.2 mmol/L, insulin:-4.7±5.4mU/L, HbA1c:-1.25±0.94%, triglycerides:-0.47±0.81mmol/L, total cholesterol:-0.67±0.69 mmol/L and LDL-cholesterol:-0.37±0.53 mmol/L, with no difference between groups (P≥0.17).

Conclusion: An energy restricted HP diet combined with RT achieved greater weight loss and more favourable changes in body composition. All treatments had similar improvements in glycemic control and CVD risk markers.

 

PROTEIN The sine qua non of Muscle-Building

PROTEIN
The sine qua non of Muscle-Building

Proteins, from the Greek word meaning "of prime importance," are definitely an important component of bodybuilders eating program. Just as glucose serves as the building block of glycogen, so are amino acids, which are the building blocks of proteins. Proteins are arguably the most important component of your cells. They're involved in formation of contractile tissue or muscle, they make up a large part of the structural component of cells, they are a part of enzymes, antibodies, blood, etc...you name it, protein is part of it.

Even though the primary function of protein is to provide the needed amino acids for maintaining an anabolic state, there are times when it may actually be used as a fuel source. This usually occurs when you're in a carbohydrate-depleted state (ex. on a low carb diet, exercising continuously for >2 hours). However, what most bodybuilders want is to maintain the absolute highest levels of anabolism or muscle building as possible. The way scientists measure this through something called nitrogen balance.

Remember that one of the components of proteins is the molecule nitrogen. In fact, nitrogen makes up about 16% of protein. So when you eat protein, you're taking in among other things nitrogen. If you want to put muscle on, you want to take in more nitrogen (i.e. protein) then you are degrading. A positive nitrogen balance exists when protein intake exceeds protein degradation. The opposite of that, a negative nitrogen balance, exists when protein intake is less than protein degradation.

HOW MUCH PROTEIN SHOULD BODYBUILDERS CONSUME?

Talk about a topic that's controversial. In my experience, I have met many physicians and dieticians who claim that "too much protein" is harmful. Sometimes I wonder if they've inhaled one too many times. There is NO SCIENTIFIC EVIDENCE that in a normal, healthy individual, consuming 2 or even 3 times the RDA for protein is harmful; unless of course, your kidney's don't work. But then again, you'd probably be strapped to a dialysis machine rather than a Pec Deck.

Darryn Willoughby, Ph.D. is the prominent expert in the field of sports nutrition and he states that "the hazards of eating a high protein diet are exaggerated; there isn't any evidence that eating 2 grams or more of protein per kilogram of body weight every day has a harmful effect. And it doesn't stress the kidneys or dehydrate you."

Suffice it to say that the RDA of 0.8 grams per kilogram body weight per day is GROSSLY INADEQUATE for bodybuilding. Although muscle protein degradation or breakdown increases during exercise, there is a significant increase in muscle protein synthesis for at least 24 hours after either resistance or endurance exercise. If you are not getting adequate protein during this time, then it would make sense that you probably will not grow or put muscle on. Current research suggests that 1.5-2.0 grams per kilogram per day is needed for those interested in packing on some muscle. I'd say jack that up a little more. You can't go wrong eating more protein.

WHICH PROTEINS SHOULD I EAT?

Basically, the protein you eat should have the entire complement of essential amino acids. The essential amino acids (i.e. you need to eat them ‘cause your body doesn't make them) include: branched-chains (valine, leucine, isoleucine), lysine, methionine, phenylalanine, threonine, and tryptophan. (Some include histidine - infants can't make it and arginine - kids can make it as well as adults). Furthermore, the body makes cysteine from methionine and tyrosine from phenylalanine; so you might say that cysteine and tyrosine are "conditionally essential." Thus, you want to eat a complete protein; one that has all of the essential amino acids. Incomplete proteins, such as from peanuts, do NOT contain all essential amino acids. So your best bet are complete sources such as milk based (i.e. whey, casein), meats, fish, etc.

Whey is better than Casein...Most of the Time

Different dietary proteins affect whole body protein anabolism and accretion and therefore, have the potential to influence results obtained from resistance training. This study looked at the effects of supplementation with two proteins, hydrolyzed whey isolate (WI) and casein (C), on strength, body composition, and plasma glutamine levels during a 10 week, supervised resistance training program. In a double-blind protocol, 13 male, recreational bodybuilders supplemented their normal diet with either WI or C (1.5 gm/kg body wt/d) for the duration of the program. What happened? The WI group achieved a significantly greater gain in lean mass than the C group and a significant drop in fat mass compared to the C group. The WI group also achieved greater improvements in strength compared to the C group in each assessment of strength. When the strength changes were expressed relative to body weight, the WI group still achieved significantly greater improvements in strength compared to the C group.(1) So in this head to head battle, whey clearly wins. But the picture gets more interesting.

Casein Protein Rocks...At Night

So does consuming protein close to bedtime actually lead to a better anabolic effect? Ever since the original paper showing that the net leucine balance over a 7 hour period after the a protein meal was more positive with casein versus whey protein, folks have suggested that consuming casein, because of its ‘slow' digesting properties is the perfect night time protein.(2) Yet as mentioned above, when you look at the only measures that matter (i.e. muscle mass and strength), whey is the winner.

Let's fast-forward to this cool study. In this one, scientists theorized that during prolonged resistance training, time-divided ingestion pattern of casein-based protein supplement is of superior efficiency in comparison with the ingestion of the same supplement immediately before each training session. This sort of puts an interesting spin on nutrient timing. In a crossover study subjects consumed the casein supplement in the morning and in the afternoon, immediately before the training session. The other supplementation scheme included 1 morning dose, whereas the second dose was ingested in the evening, 5 hours after training. One would expect that the dose taken BEFORE training would be superior; but alas, that's why they do the studies. It looks like spacing out the consumption of casein and taking it prior to bed may be a better strategy. However, what I'd suggest is to consume a fast protein (e.g. whey) pre and/or post exercise while also consuming casein before bed time. That, IMO, is the best of all strategies.
Either way, this does throw a wrench into the nutrient timing strategy in that difference proteins may in fact have applications that vary (i.e. whey may be best pre and post workout, casein at night, etc).

WHEN SHOULD I EAT PROTEIN?

Again, ideally it is best to consume a supplement with protein both immediately pre and post training. This results in a greater increase in lean body mass and 1-RM strength. The changes in body composition are due in part to a greater increase in the size of type II fibers and contractile protein content. Supplement timing represents a simple but effective strategy that enhances the adaptations desired from RE-training.(3)

Bottom line: eat a small meal every 3 hours. Make sure it's a lean protein source with a fibrous veggie and a complex carb. If you don't have time for a meal, consume any of a number of excellent Protein Rush RTDs or ZI bars (see www.vpxsports.com.)

References-Boring Science Articles Basically

1. Cribb PJ, Williams AD, Carey MF, Hayes A. The effect of whey isolate and resistance training on strength, body composition, and plasma glutamine. Int J Sport Nutr Exerc Metab 2006;16(5):494-509.
2. Boirie Y, Dangin M, Gachon P, Vasson MP, Maubois JL, Beaufrere B. Slow and fast dietary proteins differently modulate postprandial protein accretion. Proc Natl Acad Sci U S A 1997;94(26):14930-5.
3. Cribb PJ, Hayes A. Effects of supplement timing and resistance exercise on skeletal muscle hypertrophy. Med Sci Sports Exerc 2006;38(11):1918-25.

Jack Owoc’s Real White Paper! Muscle Marinade Madness

First, let's define "White Paper"

A white paper is supposed to be an authoritative scientific technical report. Unfortunately, white papers are now used as documents used by businesses as a marketing and sales tools. In all my years of research and development this is the first time I've seen a PhD bastardize the integrity of a white paper by misusing it as a marketing tool.

Therefore, in regard to Muscle Marinade a white paper is just a marketing "sales tool". And, further in the case of Muscle Marinade it is a shameless attempt to get you to purchase a product with ZERO scientific backing and riddled with non-scientific hype!

Second, who is Purus Labs that makes Muscle Marinade?
Purus Labs is one of the biggest black market dealers of bogus steroids in America unlawfully operating as a supplement company. They are using the money made from illegal sales of black market steroids to now manufacture cheap low grade supplements. Below is an e-mail that was circulated by a representative of Purus Labs attempting to increase sales of anabolic steroid cocktails: "Epol is also another great seller, it's a combination of Superdrol & Tren. The majority of our products are a combination of a precursor (prohormone) plus an actual hormone; whereas most companies only have pre-cursors".

From: Ashley Faulkner [mailto:ashley@formulifesupplements.com]
Sent: Monday, November 02, 2009 5:26 PM
To:
Subject: Purus Labs
Hi,
My name is Ashley Faulkner; I am the national sales manager for Purus Labs. I have attached cut sheets for the entire Purus Labs line. Our line has a great presence in the south and midwest regions and we are gaining momentum in the north. If you have a lot of requests for Spawn, our M 14-E is a great replacement and has double the Epistane of Spawn. Epol is also another great seller, it's a combination of Superdrol & Tren. The majority of our products are a combination of a precursor (prohormone) plus an actual hormone; whereas most companies only have pre-cursors. Everything about our company is cutting edge and high quality from the formulations down to the packaging. We have a lot of support on websites and in retail stores. However, I do monitor the website pricing two times a week to make sure they are not selling below our designated MAP pricing. I would really like to work with you on bringing Purus in and can put together a great deal for you. Please let me know what I can do to get on board with your company. I look forward to doing business with you!

Unfortunately, these renegade drug dealing supplement companies have put our industry in great jeopardy. This is clearly evident by Senator John McCain's press release this week to pass a bill that would radically alter DSHEA and turn the supplement industry upside down.

We have to take action and police our own industry. Anybody purchasing products from Purus Labs is partaking in behavior that will inevitably lead to the demise of our great dietary supplement industry. Yes, even if you personally, your store or gym or distribution center purchases a product like Muscle Marinade (that does not list steroids in the ingredient profile), you are:

1. Supporting clandestine drug labs and dealers.
2. Maybe purchasing supplements cross contaminated with anabolic steroids. 
3. Maybe purchasing product purposely infused with anabolic steroids and or other drugs --Do you honestly think that a drug dealer cares if your supplements are cross contaminated by air born steroids or steroid residue from unclean manufacturing equipment? Do you honestly think that an anabolic steroid dealer wouldn't purposely spike their Muscle Marinade with steroids?

McCain desires to radically alter DSHEA mostly to protect athletes from testing positive from taking adulterated dietary supplements. Therefore, Purus Labs and others like them need to be shut down NOW before McCain and other doping agencies attempt to shut down are entire industry!

You will notice that the Muscle Marinade white paper vehemently defends and justifies the use of the cheapest raw materials and bashes any raw materials that cost more than cheap Chinese creatine! It bashes COP (Creatinol-O-Phosphate) because COP cost roughly 20 times that of low grade creatine monohydrate. It also says that COP is NOT creatine which is scientifically inaccurate. Chemically speaking COP is deoxy-Creatine-O-phosphate. The author fails to understand chemical nomenclature and the power of such a unique bodybuilding and performance enhancing compound. The author further has failed to perform an exhaustive search of the available scientific database in regard to COP.

Creatinol-O-Phosphate, in addition to its cardio-protective effects, has been has also been shown to improve muscle development and increase the capacity of a muscle to perform physical activity. In one study, hand-grip strength was improved by Creatinol-O-Phosphate administration and while remaining unaffected in a placebo group (Nicaise J. Creatinol O-phosphate (COP) and muscular performance: a controlled clinical trial. Curr Ther Res Clin Exp. 1975, 17(6):531-4). Moreover, in another study conducted in elderly subjects, it was found that Creatinol-O- Phosphate improved muscular performance as compared to controls (Cavalieri U, Quadri A, Ghirardi F. Effects of creatinol o-phosphate on the muscle function of elderly people. The T! herapeutic Clinic. 1974, 69: 215-223).

These scientific references clearly indicate COP's ability to increase strength and muscular performance that the author failed to include in his Mental Marinaded Madness!

Creatinol-o-phosphate was discovered and by a researcher by the name of Shotte in 1928 who observed its structural similarity to creatine. In vivo COP is similar to creatine in some ways and differs in others having unique and very interesting intrinsic properties! True legends in their own mind--self proclaimed internet gurus have erroneously concluded that, "if you look at the structures (of COP) you can easily tell it's just not creatine" because these chemistry challenged clowns have compared a creatine monohydrate molecule to COP rather than comparing COP with creatine phosphate. Therefore, these internet idiots have concluded that the molecular structures of creatine monohydrate and creatinol-o-phosphate aren't similar-of course they are not similar in appearance because creatine monohydrate lacks a phosphate group. COP and creatine phosphate are very close in appearance because both compounds have a creatine and a phosphate group. Well neither does Fergilicious' back side look like Jack Kavorkian's; yet, Fergie's backside has striking similarities to J-Lo's -- no different that Creatinol-O-Phosphate's striking similarities to Creatine Phosphate. And, that is because Creatinol-O-Phosphate is really DeoxyCreatine-O-Phosphate meaning structurally there is only one Oxide atom difference between COP and Creatine Phosphate and, therefore, can be oxidized into creatine. It shares a highly similar molecular structure to creatine phosphate and is believed to be synergistic with other creatine salts as proven with the finished product, NO-Shotgun®. Human subject studies performed at Baylor University prove that NO--Shotgun yields an unprecedented 515% increase in muscle gene proteins and 1,600% increases in muscle DNA -cutting edge science that the Muscle Marinade author fails to mention that is published scientific journal data!

COP, aka N-Methyl-N-(beta-hydroxyethyl) guanidine O-phosphate (creatinol O-phosphate) has proved to possess anti-ischemic (i.e. keep oxygen levels healthy) and anti-arrhythmic (keeps heart beating with more rhythm) activities associated with improved ionic balance and heart performance. These activities are more evident in pharmacological and clinical conditions involving a hypoxic damage of the heart muscle. When injected i.m., pharmacokinetic studies have shown that absorption of COP to be complete. COP is distributed in all organs, and in particular, in the kidney, liver and heart muscle. The results of the toxicological studies confirm that COP has no side effects and seems to be well-tolerated.(1) In fact, the action of creatinol-O-phosphate on the recovery of heart muscle contraction ability after ischemia (i.e. loss of oxygen) has been shown; thus, creatinol-O-phosphate could exert its cardioprotective effect by an action on anaerobic glycolysis according to one report.(2) As far as the safety of it in humans, the acute clinical tolerance to COP was investigated in volunteer human subjects without heart or renal disease and without other serious illness. COP was administered i.v. at three different dosages, 1020 mg (group A), 2040 mg (group B) and 3060 mg (group C), in comparison with a placebo (group D). Arterial pressure, heart rate, ECG pattern and a complete blood analysis showed no change at any COP dosage, with the exception of blood phosphate, which increased in groups B and C. Cumulative urinary excretion of phosphate and creatinine and diuresis increased (i.e. they urinated more), whereas other urine parameters did not change. Therefore, COP proved to be a very well tolerated drug without any evident side effect.(3) Other studies have that COP improved rhythm disturbances, chest pains and symptoms of contractility failure.(4) COP is an intercellular buffer (a characteristic similar to that of beta-alanine) and increases anaerobic glycolysis allowing you to train longer, harder (past typical sticking and failure points) and improving eccentric contraction - the negative movement in resistance training proven to be the most effective for building muscle!

References:

1. Marzo A, Ghirardi P. Pharmacological and toxicological properties of creatinol O-phosphate. A review. Arzneimittelforschung 1979;29(9a):1449-52.
2. Godfraind T, Saleh MM. Action of creatinol-O-phosphate on the contractility changes evoked by hypoxia and ischemia in rat isolated heart. Arzneimittelforschung 1984;34(9):968-72.
3. Melloni GF, Minoja GM, Lureti GF, Merlo L, Pamparana F, Brusoni B. Acute clinical tolerance of creatinol O-phosphate. Arzneimittelforschung 1979;29(9a):1447-9.
4. Barlattani M, Guglielmi G, Mammarella A. Creatinol O-phosphate therapy in patients with inadequate coronary circulation. Double-blind clinical trial. Arzneimittelforschung 1979;29(9a):1483-5.
   

In conclusion, this is just support for one of the compounds that the author bashes in his "white paper" misuse and abuse. The bigger picture is that we as an industry have to police ourselves and shut Purus Labs down immediately before new legislation is enacted that will destroy the ethical and outstanding companies of the dietary supplement industry! The exceptional companies and leaders of high moral and ethical character that make up 98% of the dietary supplement industry need to take a united stand against the dopes and dopers whose selfishness and lawlessness threaten to destroy our industry.

Post Workout Nutrition - Better than Breakfast!

Dr. Jose Antonio tells you why post workout nutrition is key to promoting better performance and body composition. Tune in now!  

Zero Carb High Protein Oatmeal Pancakes Recipe

• 1/8 cup of buckwheat pancake mix
• 1/3 cup whole (old fashioned) oatmeal (do not use pre-cooked or "quick" oatmeal)
• 4 XL egg whites
• 1/4 cup low fat cottage cheese
• 1/2 scoop Zero Carb Vanilla Protein
• 1 TBSP chopped pecans
• 1-2 Teaspoon vanilla extract
• 1/2 Teaspoon olive oil
• 1/4 teaspoon cinnamon
• 1/8 teaspoon nutmeg 
• 1-2 packets(s) of Splenda®